BDBM29926 substituted 6-aminoquinoline-3-carbonitrile, 37

SMILES Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cn(nn4)C4CCN(CC4)C4CCC4)cc23)C#N)cc1Cl

InChI Key InChIKey=YGHNIYXOYMJYDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29926   

LigandPNGBDBM29926(substituted 6-aminoquinoline-3-carbonitrile, 37)
Affinity DataIC50: 10nMAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues 217 and 221 of GST-MEK1 was detected by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2009
Entry Details Article
PubMed