BDBM299200 N-(2-(4-Fluoroisoindolin-2-yl)pyrimidin-4-yl)-1H-indazol-5-amine::US10125144, Example 29

SMILES Fc1cccc2CN(Cc12)c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=OGFNSASCOJXZNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299200   

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandPNGBDBM299200(US10125144, Example 29 | N-(2-(4-Fluoroisoindolin-...)
Affinity DataIC50: 880nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
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Date in BDB:
3/11/2019
Entry Details
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