BDBM298451 Ethyl (4-((4-((4-(3-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxyphenyl)(methyl)phosphinate::US10125100, Example 43

SMILES CCOP(C)(=O)c1ccc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc1OC

InChI Key InChIKey=SIKCUPWQHPKKSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298451   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298451(US10125100, Example 43 | Ethyl (4-((4-((4-(3-(5-(t...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
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