BDBM298426 4-[[4-[[4-[[5-tert-butyl-3-(methanesulfonamido)-2-methoxy-phenyl]carbamoylamino]-1-naphthyl]oxy]-2-pyridyl]amino]-2-methoxy-N-methyl-N-(3-morpholinopropyl)benzamide::US10125100, Example 17(af)::US10392346, Example 17(af)::US10941115, Example 17(af)::US9751837, Example 17(af)

SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(=O)N(C)CCCN1CCOCC1

InChI Key InChIKey=IHCLBOWQUVPHBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298426   

TargetBaculoviral IAP repeat-containing protein 2 [174-256](Human)
Topivert Pharma

US Patent
LigandPNGBDBM298426(US10125100, Example 17(af) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 5nMAssay Description:p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details
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TargetGlycogen synthase kinase-3 alpha(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298426(US10125100, Example 17(af) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 680nMAssay Description:GSK 3α Method 2: This method follows the same steps as Method 1, but utilises a shorter period of mixing of the test compound (105 minutes inste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent