BDBM298352 (S)-1-((2S,4R)-1-(4-(benzyloxy)-3,5-dimethoxybenzoyl)-4-fluoropyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 2::US10611727, Example 2

SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@H](F)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=VPSURWWYROJTIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298352   

TargetProlyl endopeptidase(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298352(US10125097, Example 2 | (S)-1-((2S,4R)-1-(4-(benzy...)
Affinity DataIC50: 60.4nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetProlyl endopeptidase-like(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298352(US10125097, Example 2 | (S)-1-((2S,4R)-1-(4-(benzy...)
Affinity DataIC50: 60.4nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent