BDBM29816 4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c::CHEMBL513485

SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12

InChI Key InChIKey=ALLMHFJXFWBPDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29816   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM29816(CHEMBL513485 | 4-indolylamino-5-phenyl-3-pyridinec...)
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2009
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM29816(CHEMBL513485 | 4-indolylamino-5-phenyl-3-pyridinec...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM29816(CHEMBL513485 | 4-indolylamino-5-phenyl-3-pyridinec...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human PKCdelta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed