BDBM297548 US10118902, Example 50::US10584103, Example 50::[4-[4-(2-dimethylamino-phenyl)- piperidin-1-yl]-2-(1- trifluoromethyl-cyclopropyl)- quinazolin-6-yl]-methyl-(2- morpholin-4-yl-ethyl)-amine

SMILES CN(C)c1ccccc1C1CCN(CC1)c1nc(nc2ccc(cc12)N(C)CCN1CCOCC1)C1(CC1)C(F)(F)F

InChI Key InChIKey=GFLYFOAAPDSXCV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297548   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297548(US10118902, Example 50 | [4-[4-(2-dimethylamino-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
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TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297548(US10118902, Example 50 | [4-[4-(2-dimethylamino-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent