BDBM29749 macrocyclic peptidomimetic, 3c

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H]1CCCCCCCCCC(=O)N[C@@H](C)C(=O)N1

InChI Key InChIKey=LDOIFDPEQRPVBI-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29749   

TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)
Affinity DataIC50: 7.60E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed