BDBM29745 hydroxyethylene tripeptide inhibitor, 2a

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CCC(C)C

InChI Key InChIKey=DKWURVMIQCMWSA-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29745   

TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)
Affinity DataIC50: 3.70E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed