BDBM29686 (7-hydroxy-2-oxochromen-4-yl)methyl 2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetate::(7-oxidanyl-2-oxidanylidene-chromen-4-yl)methyl 2-(3-oxidanylidene-4H-1,4-benzothiazin-2-yl)ethanoate::2-(3-keto-4H-1,4-benzothiazin-2-yl)acetic acid (7-hydroxy-2-keto-chromen-4-yl)methyl ester::2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl ester::MLS000393940::SMR000247371::cid_5853681

SMILES Oc1ccc2c(COC(=O)CC3Sc4ccccc4NC3=O)cc(=O)oc2c1

InChI Key InChIKey=CPLUPJVUVTZVJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29686   

LigandPNGBDBM29686(2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid (7-h...)
Affinity DataIC50: 4.87E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29686(2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid (7-h...)
Affinity DataIC50: 1.96E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2009
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29686(2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid (7-h...)
Affinity DataIC50: 1.96E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2009
Entry Details
PCBioAssay