BDBM29664 (E)-2-Cyano-3-[2-(3,5-dimethyl-phenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-N-(1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-acrylamide::(E)-2-cyano-3-[2-(3,5-dimethylphenoxy)-9-methyl-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-N-(1,1-dioxo-3-thiolanyl)-2-propenamide::(E)-2-cyano-3-[2-(3,5-dimethylphenoxy)-9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl]-N-(1,1-dioxothiolan-3-yl)prop-2-enamide::(E)-2-cyano-N-(1,1-diketothiolan-3-yl)-3-[2-(3,5-dimethylphenoxy)-4-keto-9-methyl-pyrido[1,2-a]pyrimidin-3-yl]acrylamide::(E)-N-[1,1-bis(oxidanylidene)thiolan-3-yl]-2-cyano-3-[2-(3,5-dimethylphenoxy)-9-methyl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide::MLS000580923::SMR000220364::cid_5917493

SMILES Cc1cc(C)cc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(=O)NC2CCS(=O)(=O)C2)c1

InChI Key InChIKey=VDKCNZDRYRIVDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29664   

TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29664((E)-2-Cyano-3-[2-(3,5-dimethyl-phenoxy)-9-methyl-4...)
Affinity DataIC50: 6.80E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2009
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29664((E)-2-Cyano-3-[2-(3,5-dimethyl-phenoxy)-9-methyl-4...)
Affinity DataIC50: 6.80E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2009
Entry Details
PCBioAssay