BDBM2966 3-(2-cyclopropylethynyl)-4-(cyclopropylmethyl)-6-methoxy-3-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-2-one::Quinoxalinone deriv. 6k

SMILES COc1ccc2NC(=O)C(C#CC3CC3)(N(CC3CC3)c2c1)C(F)(F)F

InChI Key InChIKey=QLSGURHMEHGRRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2966   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2966(3-(2-cyclopropylethynyl)-4-(cyclopropylmethyl)-6-m...)
Affinity DataIC50: 109nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2005
Entry Details Article
PubMed