BDBM296432 6-(2-hydroxy-2- methylpropoxy)-4-(6- (6-((5- methoxypyridin-2- yl)methyl)-3,6- diazabicyclo[3.1.1] heptan-3-yl)pyridin-3- yl)pyrazolo[1,5- a]pyridine-3- carbonitrile::US10112942, Example 166

SMILES COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

InChI Key InChIKey=XIIOFHFUYBLOLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296432   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 296432BDBM296432(US10112942, Example 166 | 6-(2-hydroxy-2- methylpr...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed