BDBM29616 Dimethyl-[4-(2-methyl-5,6-dihydro-pyrazolo[1,5-c]quinazolin-5-yl)-phenyl]-amine::MLS000068419::N,N-dimethyl-4-(2-methyl-3,5-dihydropyrazolo[1,5-c]quinazolin-5-yl)aniline::SMR000015202::cid_5295075::dimethyl-[4-(2-methyl-3,5-dihydropyrazolo[1,5-c]quinazolin-5-yl)phenyl]amine

SMILES CN(C)c1ccc(cc1)C1Nc2ccccc2-c2cc(C)nn12

InChI Key InChIKey=HIBWKMQYVONBLF-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29616   

TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29616(SMR000015202 | Dimethyl-[4-(2-methyl-5,6-dihydro-p...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2009
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29616(SMR000015202 | Dimethyl-[4-(2-methyl-5,6-dihydro-p...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2009
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM29616(SMR000015202 | Dimethyl-[4-(2-methyl-5,6-dihydro-p...)
Affinity DataEC50: >1.10E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM29616(SMR000015202 | Dimethyl-[4-(2-methyl-5,6-dihydro-p...)
Affinity DataEC50:  1.08E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay