BDBM29561 1-(m-trifluorophenyl)piperazine, 8

SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)CCCC1=O

InChI Key InChIKey=QPDOXFZMEXGLGN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29561   

Target5-hydroxytryptamine receptor 1A(Rat)
Polish Academy of Sciences

LigandPNGBDBM29561(1-(m-trifluorophenyl)piperazine, 8)
Affinity DataKi:  2.60nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Polish Academy of Sciences

LigandPNGBDBM29561(1-(m-trifluorophenyl)piperazine, 8)
Affinity DataKi:  85nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Polish Academy of Sciences

LigandPNGBDBM29561(1-(m-trifluorophenyl)piperazine, 8)
Affinity DataKi:  1.20E+3nM ΔG°:  -8.40kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Polish Academy of Sciences

LigandPNGBDBM29561(1-(m-trifluorophenyl)piperazine, 8)
Affinity DataKi: >5.00E+3nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2009
Entry Details Article
PubMed