BDBM295272 6-(1-aminomethyl-3- methyl-butylamino)- 4-(6-isopropyl-5- methyl-pyridin-2- ylamino)-pyridazine- 3-carboxylic acid amide::US10112928, Compound I-15

SMILES CC(C)CC(CN)Nc1cc(Nc2ccc(C)c(n2)C(C)C)c(nn1)C(N)=O

InChI Key InChIKey=JTHXQADAFIIKLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295272   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295272(US10112928, Compound I-15 | 6-(1-aminomethyl-3- me...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
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