BDBM294503 1-(1-Methyl-2-{2-[3-methyl-2-(trifluoromethyl) imidazo[1,2-b]pyridazin-6-yl]ethynyl}-1H-imidazol-4-yl)pyrrolidin-2-one::US9586970, 24

SMILES Cc1c(nc2ccc(nn12)C#Cc1nc(cn1C)N1CCCC1=O)C(F)(F)F

InChI Key InChIKey=KBWMEOMYHWABGP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294503   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM294503(US9586970, 24 | 1-(1-Methyl-2-{2-[3-methyl-2-(trif...)Copy SMILESCopy InChI

Affinity DataIC50: 75.5nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2019
Entry Details
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