BDBM294491 1-[1-(Cyclopropylmethyl)-2-(2-{4,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}ethyl)-1H-imidazol-4-yl]pyrrolidin-2-one::US9586970, 12

SMILES Cc1cnc(C)c2nc(CCc3nc(cn3CC3CC3)N3CCCC3=O)nn12

InChI Key InChIKey=YHYZYVYMKFFWRU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294491   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM294491(US9586970, 12 | 1-[1-(Cyclopropylmethyl)-2-(2-{4,7...)Copy SMILESCopy InChI

Affinity DataIC50: 16.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2019
Entry Details
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