BDBM294483 1-(1-(Cyclopropylmethyl)-2-(2-(5, 8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)ethyl)-1H-imidazol-4-yl)pyridin-2(1H)-one::US9586970, 4

SMILES Cc1cnc(C)c2nc(CCc3nc(cn3CC3CC3)-n3ccccc3=O)nn12

InChI Key InChIKey=SINWXYZUDOWMAJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294483   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM294483(US9586970, 4 | 1-(1-(Cyclopropylmethyl)-2-(2-(5, 8...)Copy SMILESCopy InChI

Affinity DataIC50: 150nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2019
Entry Details
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