BDBM294459 US9586959, Compound 82

SMILES Clc1cnc2nc(N3CC4CCCNC4C3)c3nncn3c2c1

InChI Key InChIKey=GVAOMJUJOPOKOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294459   

TargetHistamine H3 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294459(US9586959, Compound 82)
Affinity DataIC50: 1.00E+8nMpH: 7.4 T: 2°CAssay Description:Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294459(US9586959, Compound 82)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294459(US9586959, Compound 82)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed