BDBM294429 US9586959, Compound 3

SMILES CN1CCN(CC1)c1nc2ncccc2n2cnnc12

InChI Key InChIKey=YVRBEXPZVHWNLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294429   

TargetHistamine H3 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294429(US9586959, Compound 3)
Affinity DataIC50: 1.00E+8nMpH: 7.4 T: 2°CAssay Description:Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294429(US9586959, Compound 3)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294429(US9586959, Compound 3)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed