BDBM29425 7-alkoxyisoquinoline, 35

SMILES NS(=O)(=O)c1ccc(cc1)-c1cc2ccncc2cc1OCC1CCNCC1

InChI Key InChIKey=FXFIQQYBRIHTQJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29425   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Gsk

LigandBDBM29425(7-alkoxyisoquinoline, 35)Copy SMILESCopy InChI

Affinity DataIC50: 631nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/8/2009
Entry Details Article
Copy BDB DOIPubMed
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Gsk

LigandBDBM29425(7-alkoxyisoquinoline, 35)Copy SMILESCopy InChI

Affinity DataIC50: 1.58E+4nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/8/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL