BDBM294231 US9586942, 5*

SMILES CCCS(=O)(=O)NC1CN(C1)c1ccc2CC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1

InChI Key InChIKey=CAGWOYBCTPGQGT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294231   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbvie Deutschland

Curated by ChEMBL
LigandPNGBDBM294231(US9586942, 5*)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

Curated by ChEMBL
LigandPNGBDBM294231(US9586942, 5*)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM294231(US9586942, 5*)
Affinity DataKi: <10nMAssay Description:Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 cells per well in 96 well Cytostar-T scintillation microplates (Amersha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent