BDBM29421 7-alkoxyisoquinoline, 31

SMILES C(Oc1cc2cnccc2cc1-c1ccccc1)C1CCCNC1

InChI Key InChIKey=IGEXQLRNXKQBQI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29421   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Gsk

LigandBDBM29421(7-alkoxyisoquinoline, 31)Copy SMILESCopy InChI

Affinity DataIC50: 158nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/8/2009
Entry Details Article
Copy BDB DOIPubMed
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Gsk

LigandBDBM29421(7-alkoxyisoquinoline, 31)Copy SMILESCopy InChI

Affinity DataIC50: 3.16E+3nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/8/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL