BDBM2935 6-chloro-4-(2-cyclopropylethynyl)-8-fluoro-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one::Efavirenz deriv. 4n

SMILES Fc1cc(Cl)cc2c1NC(=O)OC2(C#CC1CC1)C(F)(F)F

InChI Key InChIKey=KHCUXFYAUCRPAZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2935   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2935(6-chloro-4-(2-cyclopropylethynyl)-8-fluoro-4-(trif...)
Affinity DatapH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2005
Entry Details Article
PubMed