BDBM29345 Indomethacin-amide derivative, 15

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(C)c3ccncc3)c2c1

InChI Key InChIKey=OLIGVCMWZHUUSR-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29345   

TargetSterol 14-alpha demethylase(Trypanosoma cruzi (strain CL Brener))
Vanderbilt University

LigandPNGBDBM29345(Indomethacin-amide derivative, 15)
Affinity DataKd:  370nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed