BDBM293377 N-((1R,4r)-4-((R)-3- aminobutanamido) cyclohexyl)-5- cyclopropyl-N- phenethylisoxazole- 3-carboxamide::US10106510, Compound 41

SMILES C[C@@H](N)CC(=O)N[C@H]1CC[C@@H](CC1)N(CCc1ccccc1)C(=O)c1cc(on1)C1CC1

InChI Key InChIKey=MUTPXBRQWZOPIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293377   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293377(US10106510, Compound 41 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 5.71E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent