BDBM293309 US10106504, Example 46

SMILES Cc1nc(C)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(C2=CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key InChIKey=VELUMHVHMRYZEK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293309   

TargetGag-Pol polyprotein [489-587,Q496K](Human immunodeficiency virus type 1)
Viiv Healthcare UK (NO.5)

US Patent
LigandPNGBDBM293309(US10106504, Example 46)
Affinity DataEC50: <100nMpH: 7.55Assay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetGag-Pol polyprotein [489-587,Q496K](Human immunodeficiency virus type 1)
Viiv Healthcare UK (NO.5)

US Patent
LigandPNGBDBM293309(US10106504, Example 46)
Affinity DataEC50:  61nMpH: 7.55Assay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent