BDBM292717 US10106501, Example A1

SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(C(=O)N4CCN(CC4)C4COC4)c3Cl)cc12)C(F)(F)F

InChI Key InChIKey=YOLONXDHSMBQTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292717   

TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM292717(US10106501, Example A1)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAL4-RORgammat LBD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM292717(US10106501, Example A1)
Affinity DataIC50: 100nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent