BDBM292098 US10100048, Example 2.2

SMILES CC(C)(C)OC(=O)N1CCc2nc(ccc2C1)C1C(=O)Nc2ccc(cc12)C#N

InChI Key InChIKey=BCZALBDHNRJRON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292098   

TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292098(US10100048, Example 2.2)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
Go to US Patent