BDBM292085 4-{2-[(3R)-3-aminopiperidine-1-carbonyl]- 5-{3-methyl-3H-imidazo[4,5-b]pyridin-6- yl}-1,3-thiazol-4-yl}benzonitrile::US10100046, Example 20::US9902719, Example 20

SMILES Cn1cnc2cc(cnc12)-c1sc(nc1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1

InChI Key InChIKey=BCZXZJPTKSJCQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292085   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292085(US10100046, Example 20 | 4-{2-[(3R)-3-aminopiperid...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292085(US10100046, Example 20 | 4-{2-[(3R)-3-aminopiperid...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent