BDBM292059 2-(Difluoromethyl)-3-(7-methyl-1H-indazol-5-yl)-5-(trifluoromethyl)-2H-::US10100045, Example 30

SMILES Cc1cc(cc2cn[nH]c12)-c1n(nc2ccc(nc12)C(F)(F)F)C(F)F

InChI Key InChIKey=CGSIRALUIGGXJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292059   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292059(US10100045, Example 30 | 2-(Difluoromethyl)-3-(7-m...)
Affinity DataIC50: 0.631nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
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