BDBM29161 3-carboxamido coumarin, 11

SMILES FC(F)(F)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1

InChI Key InChIKey=JXUJVKNPEQUAAV-UHFFFAOYSA-N

Data  2 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29161   

TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

LigandPNGBDBM29161(3-carboxamido coumarin, 11)
Affinity DatapH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29161(3-carboxamido coumarin, 11)
Affinity DataIC50: 250nMAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29161(3-carboxamido coumarin, 11)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed