BDBM291366 3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-8-ylmethyl]-piperazin-1-yl}-propionitrile::US9580442, Example R::US9938290, R

SMILES N#CCCN1CCN(Cc2cnc3oc4c(nc(nc4c3c2)-c2cccc3[nH]ccc23)N2CCOCC2)CC1

InChI Key InChIKey=RKURGBLIJFFUCK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291366   

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 597nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 131nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 22nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 2.54E+3nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 597nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 131nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 22nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291366(3-{4-[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 2.54E+3nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent