BDBM291364 US9580442, Example L::US9938290, L::[2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-8-ylmethyl]-(2-methoxy-ethyl)-methyl-amine

SMILES COCCN(C)Cc1cnc2oc3c(nc(nc3c2c1)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=NGQKZORGFHCWJH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291364   

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 604nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 111nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 21nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 1.82E+3nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 604nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 111nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 21nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291364([2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 1.82E+3nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent