BDBM291363 2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-ylmethyl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine::US9580442, Example K::US9938290, K

SMILES C(N1CCOCC1)c1cnc2oc3c(nc(nc3c2c1)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=FQDZEXAWGGTCSJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291363   

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 355nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 64nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 6nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 2.61E+3nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 355nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 64nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 6nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)
Affinity DataIC50: 2.61E+3nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent