BDBM291362 2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine::US9580442, Example J::US9938290, J

SMILES CN1CCN(Cc2cnc3oc4c(nc(nc4c3c2)-c2cccc3[nH]ccc23)N2CCOCC2)CC1

InChI Key InChIKey=YWHHLIIWAUAVFS-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291362   

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 680nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 277nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 26nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 1.04E+3nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 680nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 277nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 26nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291362(2-(1H-Indol-4-yl)-8-(4-methyl-piperazin-1-ylmethyl...)
Affinity DataIC50: 1.04E+3nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent