BDBM291357 2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine::US9580442, Example E::US9938290, E

SMILES C1CN(CCO1)c1nc(nc2c3cc(cnc3oc12)-c1cccc2[nH]ccc12)-c1cccc2[nH]ccc12

InChI Key InChIKey=GQKBNRLKAFHREP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291357   

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 88nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 69nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 7nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 627nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 88nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 69nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 7nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291357(2,8-Bis-(1H-indol-4-yl)-4-morpholin-4-yl-pyrido[3&...)
Affinity DataIC50: 627nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent