BDBM291355 2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine::US9580442, Example B::US9938290, B

SMILES C1CN(CCO1)c1nc(nc2c3cccnc3oc12)-c1cccc2[nH]ccc12

InChI Key InChIKey=IYHGDFUDPYQYFM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291355   

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 159nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 19nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 6nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 317nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 159nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 19nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 6nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

LigandPNGBDBM291355(2-(1H-Indol-4-yl)-4-morpholin-4-yl-pyrido[3′...)
Affinity DataIC50: 317nMAssay Description:Please see articleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent