BDBM291324 US9580432, Example 55

SMILES Nc1ncnc2n(cc(C(=O)Nc3nc4cc(ccc4o3)-c3ccccc3)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=GOXICPHXIWDKEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291324   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291324(US9580432, Example 55)
Affinity DataIC50: 0.799nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent