BDBM291188 3-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)methyl]amino}-4-(1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)cyclobut-3-ene-1,2-dione::US9580412, Example 17

SMILES Cc1ccc(o1)C(Nc1c(Nc2cccn(C)c2=O)c(=O)c1=O)C1CCCS1

InChI Key InChIKey=LPLKAXWKZWWASO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291188   

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291188(3-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)...)
Affinity DataIC50: 384nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291188(3-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)...)
Affinity DataIC50: 44nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent