BDBM2906 (3S,5S)-7-chloro-5-(2-cyclopropylethynyl)-3-methyl-5-(trifluoromethyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-2-one::4,1-Benzoxazepinone analogue 1f

SMILES C[C@@H]1O[C@@](C#CC2CC2)(c2cc(Cl)ccc2NC1=O)C(F)(F)F

InChI Key InChIKey=QCTDQQNLOPRRMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2906   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2906((3S,5S)-7-chloro-5-(2-cyclopropylethynyl)-3-methyl...)
Affinity DataIC50: 82nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Instituto De Tecnologia Em F£Rmacos

Curated by ChEMBL
LigandPNGBDBM2906((3S,5S)-7-chloro-5-(2-cyclopropylethynyl)-3-methyl...)
Affinity DataIC50: 82nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed