BDBM29055 cambinol analog, 6xi

SMILES Oc1ccc2ccccc2c1Cc1c([nH]c(=S)[nH]c1=O)-c1cccc(F)c1

InChI Key InChIKey=MVYHGFTZIAAQEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29055   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

LigandPNGBDBM29055(cambinol analog, 6xi)
Affinity DataIC50: 3.83E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29055(cambinol analog, 6xi)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed