BDBM290303 10-Phenyl-4-(piperidin-4-yl)pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one hydrochloride::US10098883, Example 46::US10668071, Example 46

SMILES O=c1cc(C2CCNCC2)n2nc3nccc(-c4ccccc4)c3c2[nH]1

InChI Key InChIKey=OJHXCSOJNDGQLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290303   

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290303(US10098883, Example 46 | 10-Phenyl-4-(piperidin-4-...)
Affinity DataIC50: 17nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290303(US10098883, Example 46 | 10-Phenyl-4-(piperidin-4-...)
Affinity DataIC50: 17nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent