BDBM29014 (1R,5S,7R)-2-oxo-3-[(4-phenylphenyl)methyl]-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid::3-azadioxabicyclooctane derivative, 9

SMILES OC(=O)[C@@H]1O[C@H]2CN(Cc3ccc(cc3)-c3ccccc3)C(=O)[C@@H]1O2

InChI Key InChIKey=ZHSFIDWXKSAMPY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29014   

TargetMacrophage metalloelastase(Human)
University of Florence

LigandPNGBDBM29014((1R,5S,7R)-2-oxo-3-[(4-phenylphenyl)methyl]-6,8-di...)
Affinity DataIC50: 9.54E+5nM Kd: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2009
Entry Details Article
PubMed