BDBM289874 2-(Methyl-{6-[5-(2H-pyrazol-3-yl)- pyridin-2-yloxy]-naphthalen-2- ylmethyl}-amino)-ethanol::US9573957, Example 16

SMILES CN(CCO)Cc1ccc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc2c1

InChI Key InChIKey=QRBWTWIINMBUNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289874   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289874(2-(Methyl-{6-[5-(2H-pyrazol-3-yl)- pyridin-2-yloxy...)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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