BDBM28926 (2S)-N-(5-chlorothiophen-2-yl)-5,5,5-trifluoro-1-hydroxy-3-(2,2,2-trifluoroethyl)pentane-2-sulfonamido::Begacestat analogue, 10

SMILES OC[C@@H](NS(=O)(=O)c1ccc(Cl)s1)C(CC(F)(F)F)CC(F)(F)F

InChI Key InChIKey=CJEZEJKUSJGLHH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28926   

LigandPNGBDBM28926((2S)-N-(5-chlorothiophen-2-yl)-5,5,5-trifluoro-1-h...)
Affinity DataEC50:  16nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed