BDBM289102 6-(4-{[3-(Difluoromethyl)pyridin-2-yl]oxy}-2-methylphenyl)-1-ethyl-5-methylpyrimidine-2,4(1H,3H)-dione (12)::US10093655, Example 12

SMILES CCn1c(-c2ccc(Oc3ncccc3C(F)F)cc2)c(C)c(=O)[nH]c1=O

InChI Key InChIKey=HEOSBLIXNZADTA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289102   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289102(US10093655, Example 12 | 6-(4-{[3-(Difluoromethyl)...)
Affinity DataKi:  55.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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