BDBM289098 (+)-1,5-Dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)pyrimidine-2,4(1H,3H)-dione (8)::US10093655, Example 8

SMILES Cc1cc(ccc1C2=C(C(=O)NC(=O)N2C)C)Oc3c(cccn3)C(F)(F)F

InChI Key InChIKey=AKQXQLUNFKDZBN-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289098   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent

LigandBDBM289098(US10093655, Example 8 | (+)-1,5-Dimethyl-6-(2-meth...)Copy SMILESCopy InChI

Affinity DataKi:  21nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
1/22/2019
Entry Details
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PDB3D Structure (crystal)
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