BDBM289019 US10092570, Example 20::US10646492, Example 20::US9730939, Example 20::US9932341, Example 20

SMILES COc1c(cc(Cl)c(C)c1-c1cnn(CCO)c1)C(C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=BXONZXFPKQOFNN-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 289019   

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 125nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 10nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from PerkinElmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 10nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from PerkinElmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 125nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from PerkinElmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 125nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

LigandPNGBDBM289019(US10092570, Example 20 | US9730939, Example 20 | U...)
Affinity DataIC50: 125nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent